| Biography |
|---|
| My name is Juliet Daet, a Grade 12 student from Winnipeg, Manitoba. I've been involved in science fairs since I was in Grade 4, and my fascination with research and innovation has only expanded since then. The science fair experience has allowed me to blossom into the passionate young scientist that I am today. In addition to being a student researcher, I am also an avid public speaker and journalist for my school newspaper. It was also my pleasure to help coordinate my school science fair, and play a part in the mentoring of junior budding scientists. I plan on obtaining a biochemistry degree, and hopefully pursue medical studies. |
| Juliet Daet
Inhibition of Cell Growth by Polyamine Analogues in Breast Cancer
| Division: | Life Sciences / None | | Category: | Senior | | Region: | Manitoba Schools Science Symposium | | City: | Winnipeg, MB | | School: | St. Mary's Academy | | Abstract: | Polyamines are vital for DNA synthesis and cell growth. Diethylnorspermine (DENSPM), is a polyamine analogue which causes cellular events which inhibit cell growth. Effects of DENSPM were measured in MCF7 cells, which lack or overexpress the HER2 growth factor. A reduction in both cell numbers and ERa expression was observed, suggesting that DENSPM could be a new approach to cancer therapy. |
| Awards | Value | The University of Western Ontario Scholarship
Bronze Medallist - $1000 Entrance Scholarship
Sponsor: University of Western Ontario | $1 000.00 | University of Ottawa Entrance Scholarship
Senior Bronze Medallist - $1000 Entrance Scholarship
Sponsor: University of Ottawa | $1 000.00 | Bronze Medal - Health Sciences
Senior
Sponsor: Canadian Institutes of Health Research | $300.00 | | Total | $2 300.00 | |
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