Biographie |
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My name is Rebecca Todesco and I am a grade eleven student. I have been participating in my local Science Fair since the sixth grade. My previous projects have been in the fields of engineering, chemistry, health sciences and computer sciences. As a member of my schools Debate Team, my partner and I placed second in Provincials and attended the National Conference in Halifax two years ago. I enjoy playing the flute in my High School Concert Band. I am looking forward to an exciting week at the Canada Wide Science Fair. |
| Rebecca Todesco Airborne Attack
Défi: | Santé | Catégorie: | Sénior | Région: | Calgary Youth | Ville: | Calgary, AB | École: | Queen Elizabeth Junior Senior High School | Sommaire: | Alternaria alternata causes asthma but its allergenic mechanism is unknown. I hypothesized that A. alternata contains serine proteinases that activate proteinase-activated receptors (PARs). I used enzyme-activity assays, zymography and activity-based probes to identify a trypsin-like enzyme. I found that A. alternata can activate PAR2 to stimulate calcium signalling. This concludes that A. alternata contains a trypsin-like serine proteinase that via PAR2 activation accentuates allergenic activity. |
Prix | Valeur | Prix d'excellence - Senior Médaille d'argent Sponsor: Sciences jeunesse Canada | 700,00 $ | Bourses d'admission de la Faculté des sciences de l’Université Dalhousie Médaillé d’argent, sénior - Bourse d'admission de 2 500 $ Sponsor: Université Dalhousie, Faculté des sciences | 2 500,00 $ | Prix d'admission en sciences de UBC (Vancouver) Médaillé d’argent, sénior - Bourse d'admission de 2 000 $ Sponsor: The University of British Columbia (Vancouver) | 2 000,00 $ | Bourse d’études de l’Université Western Ontario Médaillé d’argent - Bourse de début d’études de 2 000 $ Sponsor: Université Western Ontario | 2 000,00 $ | Bourse d'admission de l'Université d'Ottawa Médaillé d’argent, sénior - Bourse d'admission de 2 000 $ Sponsor: Université d'Ottawa | 2 000,00 $ | Total | 9 200,00 $ | |