| Harry Zhou DNA Damage Induced Cell Death in Breast Cancer Cells That Differ in p53 Status
Division: | Biotechnologie | Catégorie: | Sénior | Région: | Calgary Youth | Ville: | Calgary, AB | École: | Western Canada Senior High School | Sommaire: | I investigate the effect of p53 status on breast tumor cell survival after exposure to IR, and how inactivation of p53, ATM or DNA-PK contributes to radiotoxicity in breast tumor cells. I found that inhibition of p53 or DNA-PK sensitized p53 wild-type MCF7 cells to IR but had no effect on p53 mutant MDA-MB-231 cells; inhibition of ATM sensitized both cell lines to IR. |
Prix | Valeur | Prix Innovation Petro-Canada décernés par les pairs - Senior Ouest du Canada Sponsor: Pétro-Canada | 200,00 $ | Bourse d’études de l’Université Western Ontario Médaillé de bronze - Bourse de début d’études de 1 000 $ Sponsor: Université Western Ontario | 1 000,00 $ | Médaille de bronze - Biotechnologie et les sciences pharmaceutiques Sénior Sponsor: Fondation pour la recherche en santé de Rx&D | 300,00 $ | Total | 1 500,00 $ | |