| Biography |
|---|
| I first became interested in antivirals following the 2009 H1N1 pandemic flu. The flu virus is slowly evolving to become more resistant to our current antivirals and new ones need to be developed. This is where my research comes in. After finishing the algorithm presented in my project, I will be using it to develop and test antivirals that I have proposed. This kind of research is exciting because you can see its significance for the real world. My two pieces of advice for other students pursuing research are: work hard and have fun. The most pressing scientific issue of the day is the threat of a flu pandemic due to the H5N1 virus as it is resistant to all currently available antivirals. |
| Eric LeGresley
Computational Methods for the Screening of Novel Neuraminidase Inhibitors
| Challenge: | Innovation | | Category: | Senior | | Region: | Fraser Valley | | City: | Chilliwack, BC | | School: | St John Brebeuf | | Abstract: | Influenza viruses cause illness ranging from “the flu” to deadly pandemics. All available anti-influenza agents target viral neuraminidase. By inhibiting this enzyme, these agents prevent new viruses from proliferating. Influenza immunity to these agents is increasing. It is of interest, then, to discover more resilient inhibitors. This research explores the use of Molecular Dynamics simulations to screen potential next-generation drug candidates. |
| Awards | Value | The Manning Innovation Achievement Award
Sponsor: Ernest C. Manning Awards Foundation | $500.00 | The Manning Innovation Achievement Award
and $4000 Manning Young Canadian Innovation Award
Sponsor: Ernest C. Manning Awards Foundation | $4 000.00 | Challenge Award - Innovation
Senior
Sponsor: Research In Motion | $1 000.00 | Excellence Award - Senior
Gold Medal
Sponsor: Youth Science Canada | $1 500.00 | Dalhousie University Faculty of Science Entrance Scholarship
Senior Gold Medallist - $5000 Entrance Scholarship
Sponsor: Dalhousie University, Faculty of Science | $5 000.00 | UBC Science (Vancouver) Entrance Award
Senior Gold Medallist - $4000 Entrance Scholarship
Sponsor: The University of British Columbia (Vancouver) | $4 000.00 | University of Manitoba Entrance Scholarship
Senior Gold Medallist - $5000 Entrance Scholarship
Sponsor: University of Manitoba | $5 000.00 | University of Ottawa Entrance Scholarship
Senior Gold Medallist - $4,000 Entrance Scholarship
Sponsor: University of Ottawa | $4 000.00 | Western University Scholarship
Gold Medallist - $4000 Entrance Scholarship
Sponsor: Western University | $4 000.00 | Platinum Award - Best Senior Project
Sponsor: Research In Motion | $5 000.00 | | Total | $34 000.00 | |
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