Biography |
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My name is Krish Joshi, and I am a Grade 9 student from Robert Bateman HS in Burlington, Ontario, completing the International Baccalaureate (IB) program. This is my second CWSF, I was awarded a silver medal last year. My scientific interests lie in medicine, botany, and microbiology. More specifically, I am fascinated by microbial biofilm formation, which gave inspiration for my project. The link between bacterial biofilms and antibiotic resistance is important to understand, and is something that I hope to communicate through my project. I would like to continue my project by testing the treatment against infected medical devices. I am also a member of the New York Academy of Sciences, through which I collaborate internationally with other students and professionals in STEM on projects ranging from climate change to malnutrition in developing countries. In school, I am involved in Model UN, and have competed provincially for DECA. When I’m not involved in STEM/school-related activities, I enjoy listening to music, reading, and playing competitive table tennis. My advice for aspiring science fair participants is to not only choose a topic you’re passionate about, but to challenge yourself, and even step outside of your comfort zone just a little. |
| Krish Joshi Tackling Pseudomonas Biofilm Resistance: Using Bacteriophage-Phenolics Synergy
Challenge: | Discovery | Category: | Intermediate | Region: | Bay Area | City: | Waterdown, ON | School: | Robert Bateman H.S. | Abstract: | The aim of this project was to see whether cell-membrane disrupting grapeseed phenolics could synergize with bacteriophages to reduce biofilm formation in Pseudomonas aeruginosa, a multi-drug resistant pathogen that accounts for 10% of all hospital-acquired infections. In this experiment, grapeseed phenolics potentiated the lytic action of bacteriophage. In clinical settings, this synergy could be used to effectively treat a variety of these resistant superbug infections. |
Awards | Value | Excellence Award - Intermediate Bronze Medal Sponsor: Youth Science Canada | | Western University Scholarship Bronze Medallist - $1000 Entrance Scholarship Sponsor: Western University | $1 000.00 | Total | $1 000.00 | |