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CWSF 2013 - Lethbridge, Alberta

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Biography
My name is Brian Laight. I am a grade 12 student at All Saints Catholic High School in Kanata, Ontario. I have many interests and have dabbled in everything from computer coding to auto mechanics, from composing and playing music to deep science inquiry. I play Rugby and Hockey competitively where I've captained on my school Rugby team two years in a row. Sports are a large portion of my life. I’ve been playing some sort of competitive sport since the age of 6. I have also been involved in humanitarian trips, where recently I’ve helped build a school on a batey in the Dominican Republic. The inspiration for my CWSF project came from my family. Many of my family members have been affected by cancer and my love for the immune system helped guide my focus on using viruses. For further investigations, I will continue my work in Dr. John Bell’s lab where I will help work towards making the therapy a potential reality. For future students who are interested in doing a project but not sure, I highly recommended jumping at the opportunity. It’s an amazing experience and you gain valuable skills as an added benefit. Do it!

Brian Laight


A Sindbis Virus short-hairpin RNA Screen to Increase Virus Replication in Cancer
Challenge:Health
Category:Senior
Region:Ottawa
City:Ottawa, ON
School:All Saints H.S.
Abstract:This cancer therapy utilizes an oncolytic virus modified to express short-hairpin RNAs, where each unique hairpin targets and suppresses multiple genes in the cell. If the gene suppressed is anti-viral, the virus will grow and spread more easily throughout the cancer. This allows for the virus to grow better, and for identification of the anti-viral gene, allowing for future research of oncolytic viruses and cancer.

Awards Value
The Manning Innovation Achievement Award
Sponsor: Ernest C. Manning Awards Foundation
$500.00
Excellence Award - Senior
Silver Medal
Sponsor: Youth Science Canada
$300.00
Dalhousie University Faculty of Science Entrance Scholarship
Senior Silver Medallist - $2500 Entrance Scholarship
Sponsor: Dalhousie University, Faculty of Science
$2 500.00
UBC Science (Vancouver) Entrance Award
Senior Silver Medallist - $2000 Entrance Scholarship
Sponsor: The University of British Columbia (Vancouver)
$2 000.00
University of Ottawa Entrance Scholarship
Senior Silver Medallist - $2000 Entrance Scholarship
Sponsor: University of Ottawa
$2 000.00
Western University Scholarship
Silver Medallist - $2000 Entrance Scholarship
Sponsor: Western University
$2 000.00
Total$9 300.00