| Biography |
|---|
| My name is Justin Lin and I am in Grade 12 at SJR school in Winnipeg, Manitoba. My hobbies include playing piano and debating. In my spare time, I do a lot of volunteering at various organizations, although I especially enjoy peer tutoring. I also play sports such as basketball, soccer and ultimate frisbee. I hope to pursue a career in medicine or research. This will be my third and final year at CWSF. After doing two years of cardiovascular research, I decided to try something new this year by working in a neuroscience lab. My project developed a new strategy to target ALS, a devastating neurodegenerative disease that results in death 3-5 years after diagnosis. My results are very promising and my lab is now testing the peptide-based treatment on ALS mouse models. To any other students thinking about doing a project, I would recommend following your passions and finding a mentor who is willing to work closely with you. It is also important to have faith in yourself and persevere; I believe that the research conducted by high school students can change the world! |
| Justin Lin
Peptide-Directed Knockdown of Misfolded SOD1 by Chaperone – Mediated Autophagy
| Challenge: | Health | | Category: | Senior | | Region: | Manitoba Schools Science Symposium | | City: | Winnipeg, MB | | School: | St. John's Ravenscourt School | | Abstract: | ALS is a neurodegenerative disease that results in death 3-5 years following diagnosis. Currently, there is no cure or definitive diagnostic test for ALS. This project investigates two novel techniques: firstly, we demonstrate the potential of our modified ELISA technique as a diagnostic tool. We also show our TAT-CT4-CTM peptide's ability to knock down ALS-associated misfolded SOD1; this peptide could be a cure for ALS. |
| Awards | Value | Canadian Society for Clinical Chemists Award
Senior
Sponsor: Canadian Society for Clinical Chemists | $1 000.00 | Youth Can Innovate Awards
Senior
Sponsor: The Gwyn Morgan and Patricia Trottier Foundation | $1 000.00 | Youth Can Innovate Awards
Senior
Sponsor: The Gwyn Morgan and Patricia Trottier Foundation | $7 000.00 | Excellence Award - Senior
Gold Medal
Sponsor: Youth Science Canada | $250.00 | Dalhousie University Faculty of Science Entrance Scholarship
Senior Gold Medallist - $5000 Entrance Scholarship
Sponsor: Dalhousie University, Faculty of Science | $5 000.00 | UBC Science (Vancouver) Entrance Award
Senior Gold Medallist - $4000 Entrance Scholarship
Sponsor: The University of British Columbia (Vancouver) | $4 000.00 | University of Manitoba Entrance Scholarship
Senior Gold Medallist - $5000 Entrance Scholarship
Sponsor: University of Manitoba | $5 000.00 | University of Ottawa Entrance Scholarship
Senior Gold Medallist - $4,000 Entrance Scholarship
Sponsor: University of Ottawa | $4 000.00 | Western University Scholarship
Gold Medallist - $4000 Entrance Scholarship
Sponsor: Western University | $4 000.00 | | Total | $31 250.00 | |
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