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Inhibition of EZH2 in Neuroblastoma Cells
| Challenge: | Health | | Category: | Intermediate | | Region: | | | City: | , | | School: | | | Abstract: | Neuroblastoma is one of the deadliest pediatric cancers. Enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase involved in methylation, a cellular process used to silence genes. EZH2 was targeted using the drug 3 deazaneplanocin A (DZNep) in a drug cytotoxicity assay. In the assay I confirmed the inhibition of neuroblastoma cell growth and apoptosis was confirmed through western blot protein analysis. |
| Awards | Value | Excellence Award - Intermediate
Silver Medal
Sponsor: Youth Science Canada | | Western University Scholarship
Silver Medallist - $2000 Entrance Scholarship
Sponsor: Western University | $2 000.00 | | Total | $2 000.00 | |
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