| Biographie |
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| Lucas Penny is a passionate grade 10 student, scientist and athlete. He has been actively involved with science all of his life. His past scientific work has included researching TrkB, which plays a crucial role in development of brain networks, to study in a mouse model of autism spectrum disorder (ASD). Lucas is also on the rowing team for school. During his grade 9 year, he won gold with his crew in the Canadian National Secondary School Regatta. Aside from athletics, he is a member of the Education Minister’s Student Advisory Council, and is playing level 8 Royal Conservatory of Music. At school, Lucas is the President of the DECA club, a member of the Student Council, and on the committee for Relay for Life. Lucas hopes to pursue a career in medicine and believes that being involved with science fair is an incredible way to contribute to his learning and society at large. |
| Lucas Penny
Rhomboid Protease 4 mRNA Expression In A Mouse Model of Alzheimer's Disease
| Défi: | Santé | | Catégorie: | Intermédiaire | | Région: | Niagara | | Ville: | Grimsby, ON | | École: | Grimsby S.S. | | Sommaire: | Rhomboid-related protein 4 is a protease that cleaves the Amyloid Precursor Protein (APP). However, mutations in APP follow a separate process to produce toxic Amyloid-β. Excess of Amyloid-β in the brain is one of the primary markers of Alzheimer’s disease. In this study, transgenic APP23 mice that over-express mutated APP were used as a partial model of Alzheimer’s disease to test Rhomboid 4 expression. |
| Prix | Valeur | Prix d'excellence - Intermédiaire
Médaille de bronze
Sponsor: Sciences jeunesse Canada | | Bourse d’études de Western University
Médaillé de bronze - Bourse d'admission de 1 000 $
Sponsor: Université Western | 1 000,00 $ | | Total | 1 000,00 $ | |
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