| Biography |
|---|
| Hi! My name is Ansh Goyal, and I am a Grade 12 International Baccalaureate student studying at Colonel By Secondary School in Ottawa, Ontario. I am an avid photographer, and enjoy nature photography. I also love tennis, and play every moment I get (and yes, I support Federer!). In my community, I volunteer with the Ottawa Paramedic Service helping to providing medical first aid at events across the city, and am also a founding member of a youth-run developing non-profit, Castlestone, that hopes to eliminate poverty and homelessness in Ottawa-Gatineau. Nevertheless, I am still a scientist at heart. After my grandmother’s diagnosis with Parkinson’s disease, I found myself reading about the disease from the scientific community’s perspective. Eventually, I formed my own ideas and was able to implement them at the University of Ottawa. In the future, I hope to continue to study microRNA – I truly believe that microRNA could lead to a new revolution in cellular medicine. To other young scientists, I advise you to simply read. Find a topic that captivates you, and just keep going. You’re bound to discover discrepancies and ask questions- questions that can lead to the “next big thing”. Cheers! |
| Ansh Goyal
LRRK2 controls alpha-synuclein levels via microRNAs in Parkinson’s disease
| Challenge: | Health | | Category: | Senior | | Region: | Ottawa | | City: | Ottawa, ON | | School: | Colonel By S.S. | | Abstract: | Lewy bodies are protein aggregates, mostly composed of alpha-synuclein, that are related to the death of dopaminergic neurons in Parkinson’s disease (PD) patients. This project builds on existing cancer and PD research to discover an alternate pathway regulating alpha-synuclein. By using siRNA and miRNA inhibitors, it was found that decreased gene expression of LRRK2 downregulates microRNA-7 levels, which in turn upregulates alpha-synuclein. |
| Awards | Value | Excellence Award - Senior
Bronze Medal
Sponsor: Youth Science Canada | | University of Ottawa Entrance Scholarship
Senior Bronze Medallist - $1000 Entrance Scholarship
Sponsor: University of Ottawa | $1 000.00 | Western University Scholarship
Bronze Medallist - $1000 Entrance Scholarship
Sponsor: Western University | $1 000.00 | | Total | $2 000.00 | |
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