| Biographie |
|---|
| My name is James Iansavitchous and I am a grade 11 student attending A.B. Lucas Secondary School. Apart from participating in science fairs, I also regularly write national and international math contests. I enjoy playing chess, and am actively involved in teaching chess to younger kids, organizing tournaments, as well as competing at provincial level competitions myself. In school, I am involved with our HOSA chapter, chess club, and Science Olympics club. Taking concepts learned in the classroom and applying them motivated me to work in a lab setting. With this project, I hope to further investigate effective routes of treatment for n-acetylcysteine in B-ALL. |
| James Iansavitchous
B-ALL Leukemia Treatment: Exploiting Dependency on ROS to Prevent Proliferation
| Défi: | Santé | | Catégorie: | Sénior | | Région: | Thames Valley | | Ville: | London, ON | | École: | A.B. Lucas S.S. | | Sommaire: | Investigation of genetic alterations in important antioxidant response and repair pathways in leukemic B-cells revealed a dependency in maintaining a state of oxidative stress. N-acetylcysteine effectively prevented rapid growth of the cells through reactive oxygen species scavenging, a safer mechanism than existing treatments. With established uses in the healthcare system, N-acetylcysteine can be efficiently repurposed for B-cell acute lymphoblastic leukemia treatment. |
| Prix | Valeur | Bourse de recherche de premier cycle de l’Université d’Ottawa
Sénior
Sponsor: Université d'Ottawa, Faculté des sciences | 10 000,00 $ | Prix d'excellence - Senior
Médaille de bronze
Sponsor: Sciences jeunesse Canada | | Bourse d'admission de l'Université d'Ottawa
Médaillé de bronze, sénior – Bourse d’admission de 1 000 $
Sponsor: Université d'Ottawa | 1 000,00 $ | Bourse d’études de Western University
Médaillé de bronze - Bourse d'admission de 1 000 $
Sponsor: Université Western | 1 000,00 $ | | Total | 12 000,00 $ | |
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