| Biography |
|---|
| My name is Anika Gupta and I am a Grade 9 student. I love being active by participating in various recreational sports. I am an avid runner. My hobbies include cooking, baking, reading and playing music. I am fascinated by the complexities of the human brain and would like to do my small part in contributing to the scientific community. After seeing PD controlling my grandpa's body, I would hope that this research could one day be developed into a treatment to help him. My advice to keen science students would be to find something that they love and to never give up. |
| Anika Gupta
A Novel Approach to Protect Dopamine Neurons Using a Peptide and Trophic Factor
| Challenge: | Health | | Category: | Intermediate | | Region: | Bay Area | | City: | Dundas, ON | | School: | Westdale S.S. | | Abstract: | The neuroprotective properties of two novel agents, MANF/CDNF neurotrophic factor, and TP5 synthetic peptide have been tested in a worm model of Parkinson’s disease (PD). The effects of these two factors on dopaminergic neurons were examined by a combination of mutant analysis and transgenic studies. Both agents suppressed age-dependent as well as oxidative stress-induced neurodegeneration, demonstrating their potentials as effective drugs for PD treatments. |
| Awards | Value | Excellence Award - Intermediate
Silver Medal
Sponsor: Youth Science Canada | | Western University Scholarship
Silver Medallist - $2000 Entrance Scholarship
Sponsor: Western University | $2 000.00 | | Total | $2 000.00 | |
Print/Download as PDF