The damage colgate and crest toothpaste cause on pig skin
Jasleen Bahia, Priya Chera
David Thompson
Floor Location : M 020 D

Everyone uses toothpaste, especially Colgate and Crest, so if they are causing damage in people's mouths, we need to figure out why. Many people complained about the burning, swelling, and blisters in their mouths that was caused by these two toothpastes, and we wanted to figure out why this occurs. After doing lots of research we concluded that propylene glycol, sodium lauryl sulfate, and tetrasodium pyrophosphate were the three ingredients that caused the damage. This is because according to our research, all three of these ingredients are skin irritant. We also conducted a separate experiment using regular toothpaste so that it would be easier to compare the damage with the whitening toothpaste. When we tested the regular toothpaste, there was no visible damage to the pig skin, but when we tested the whitening toothpaste, there were many little white specks that showed the damage in the skin. The pig skin with Colgate Optic White toothpaste had a high concentration of small white specks whereas the pig skin with Crest toothpaste had a low concentration of large white specks. We only used the pig tissue to test this because pig skin is the most similar model we could find to human skin. We were not able to see the damage very clearly so we decided to use methylene blue which helped reveal the damaged cell membranes in the pig skin.