The Efficiencies of Natural Remedies Against Fungal Infections
Ariel Moon
York House School
Floor Location : M 065 H

Fungi is a one of six types of microorganisms which can cause serious infections and diseases. According to the Global Action Fund for Fungal Infections, annually over 300 million people suffer serious fungal infections around the world. A proper treatment is vital, but pharmaceutical fungicides, pesticides that fight fungal infections, often come with adverse effects as serious as anaphylaxis. Furthermore, a need for a different solution to fungal infections is necessary with the urgency of an increasing amount of antimicrobial resistance, especially in the fungi kingdom. The efficiencies of these pharmaceutical fungicides that we depend on is decreasing, making for a rapid increase in demand for a treatment against fungal infections. Therefore, I tested the efficiencies of natural substances (Origanum vulgare, Coco nucifera, Citrus paradisi) and pharmaceutical fungicides observing the carbon dioxide production of Saccharomyces cerevisiae, a safe fungus known as baker's yeast that will mimic a fungal infection. This single-celled microscopic yeast produces energy to reproduce by feeding off of sugar, and in return gives off wastes in the form of ethanol and carbon dioxide. This process is called ethanol fermentation. Single-celled means to have only one cell. Fungi are mostly multicellular, however, yeast, a subcategory of fungi, are single-celled. They multiply as the daughter cell divides (called budding) off of the parent cells. From this budding process, scars are left to indicate where the daughter cell split. As the Saccharomyces cerevisiae organisms multiply, they use more energy resulting in more waste. I will be using a carbon dioxide sensor to observe the amount of carbon dioxide produced, which is a direct relationship with its reproduction. My end results showed that the natural substances blocked the production of carbon dioxide better. In our world today, new information is constantly sought out to ameliorate the everyday lives of humans. A new solution to fungal infections is vital, and the usage of natural substances as a treatment is healthier, safer, and in fact a huge economic relief compared to the expensive pharmaceutical drugs, its efficiencies show much hope in the quest for a new weapon against fungal infections.