Blood Flood- Blood pH(Molarity) vs. Calcium Level
Ah Jin (Angela) Yoo
Heritage Woods Secondary
Floor Location : S 004 H
The blood flowing out from a cut finger or a nose eventually ceases. The time of cessation is influenced by various attributes of blood. The body’s response to stopping blood loss is called blood clotting or coagulation. Hemophilia is a serious genetic disorder debilitating the body’s ability to clot blood, thereby resulting in excessive bleeding. Hemophilia is caused by blood’s lack of calcium. Acidosis is an excessively acidic condition of bodily fluids and tissues. There are rare cases where people have both conditions, acidosis and hemophilia. This project aims to explore the possible relationship between blood pH level and the amount of calcium platelets needed for blood coagulation. This experiment was conducted with two samples; one representing patients with hemophilia and normal blood pH level, and the other representing patients with hemophilia and acidosis. Various molarities of calcium chloride was used to find the critical molarity for coagulation. The difference in critical molarity relates to how much calcium is needed for each patient. It is important to find the right balance between pH and calcium using the results, because extreme numbers of either variable can be detrimental to health. Our experimental results show that the critical molarity of Sample A (normal pH-7.40) is lower than Sample B (acidosis patient-7.35). Using our results, we propose that, higher acidity in blood requires higher calcium concentration for coagulation to occur. Results from the experiment can be further researched in a better research environment to develop potential cures and treatment.