Low-Cost, Point-of-Care Skin Cancer Detection
Nick Murray
Templeton
Floor Location : S 073 N

Currently, there is not a low-cost and point-of-care test to detect and stage skin cancers. Almost all skin cancer diagnosis research is focused on developing solutions for people living in developed countries, and current methods require multiple trips to the dermatologist and a biopsy. Previously, Aberg. Et, Al reported that it was possible to detect and diagnose skin cancers and diseases with clinically relevant accuracy by measuring their electrical impedance at a frequency of 10 kHz (the effective resistance of an electric circuit to alternating current, arising from the combined effects of ohmic resistance and reactance). This project builds upon that research proposes the first ever low-cost and portable device able to detect and stage skin cancers and diseases by their electrical impedance. The device uses a low-cost electronics board, a 3D printed body and depth regulator, along with low-cost needles used for injecting insulin to measure impedance. Due to the lack of availability of human subjects, the electrical and mechanical properties of skin and skin diseases were recreated using hydrogels of differing NaCl molarity and viscoelastic polymers with different elastic moduli and stiffness’s. Results show that this device and the data analysis software that was created can detect skin cancers and diseases, along with their stage at an average of 98% precision. In conclusion, this prototype shows great potential to be used for a variety of applications after it is more rigorously tested in animal and eventually human trials. The primary application would be as a low-cost and point-of-care test for detecting skin cancer without the need for a dermatologist.