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CWSF 2012 - Charlottetown, Prince Edward Island

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Laura - My name is Riyeon Kim and I am currently enrolled Fort Richmond Collegiate, completing grade 12. I am involved in many school and community activities. I am very interested in Health Science, which led me to get involved in research projects and volunteering at hospital. I received an Overall Best Award in Manitoba with the research project I worked on in 2012. Considering my interest, I am planning to attend Faculty of Life Science in University. This year, our project is on an effective screening tool to diagnose colorectal cancer. This project was inspired by a scientific article dealing with cancers in Canada. In our project, we identified several nuclear matrix proteins that were more abundant in the absence of TP53. The next step in our experiment was to compare these samples to a healthy sample and compare between more cell lines and use more samples. After future experiments, TP53 is served as a marker for colorectal cancer. The projects like this always starts from curiosity, so I recommend that other students should be exposed to science through reading articles or joining a lab, so they can find or keep their passion in the fields of science.
Ashley - My name is Ashley Bell. I am a grade 11 student at Fort Richmond Collegiate in Winnipeg, Manitoba. This is my first year attending the Canada Wide Science Fair. I worked on a project with my partner Laura Kim. Our project is called Using Nuclear Matrix Proteins to Detect Colorectal Cancer Cells. We participated in the Sanofi BioGENEius Challenge Canada with it, as well as the Manitoba Schools’ Science Symposium, which has led us to the CWSF. This project was inspired out of curiosity to improve standard testing for colorectal cancer. To me, colorectal cancer seemed like a very curable disease. I never felt trouble by it, until I read a fact last year that it was the second leading cause of cancer death in Canada. This pushed me to look into research in this field. Early detection of colorectal cancer improves mortality rates drastically. Further research with this project could lead to a new serum test that could detect colorectal cancer in its earliest stages without invasive screening techniques. For students considering a project, I would suggest to simply look around for it. Inspiration comes from curiosity, so learn to question what you read. Then, start investigating!

Laura Kim, Ashley Bell

Using Nuclear Matrix to Detect Colorectal Cancer Cells
Region:Manitoba Schools Science Symposium
City:Winnipeg, MB
School:Fort Richmond Collegiate
Abstract:Fecal Occult Blood Tests are the first tests used for detecting colorectal cancer in Manitoba. The sensitivity of this test could be improved upon. This project looked at a possible serum test using nuclear matrix proteins from colorectal cancer cells with TP53, a tumor suppressor, and without TP53. These samples were compared on a 1D and 2D PAGE, revealing proteins in the absence of TP53.

Awards Value
Excellence Award - Senior
Silver Medal
Sponsor: Youth Science Canada
Dalhousie University Faculty of Science Entrance Scholarship
Senior Silver Medallist - $2500 Entrance Scholarship
Sponsor: Dalhousie University, Faculty of Science
$2 500.00
UBC Science (Vancouver) Entrance Award
Senior Silver Medallist - $2000 Entrance Scholarship
Sponsor: The University of British Columbia (Vancouver)
$2 000.00
University of Ottawa Entrance Scholarship
Senior Silver Medallist - $2000 Entrance Scholarship
Sponsor: University of Ottawa
$2 000.00
Western University Scholarship
Silver Medallist - $2000 Entrance Scholarship
Sponsor: Western University
$2 000.00
Total$9 200.00