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ESPC 2019 - Fredericton (Nouveau-Brunswick)

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My name is James Iansavitchous and I am a grade 11 student attending A.B. Lucas Secondary School. Apart from participating in science fairs, I also regularly write national and international math contests. I enjoy playing chess, and am actively involved in teaching chess to younger kids, organizing tournaments, as well as competing at provincial level competitions myself. In school, I am involved with our HOSA chapter, chess club, and Science Olympics club. Taking concepts learned in the classroom and applying them motivated me to work in a lab setting. With this project, I hope to further investigate effective routes of treatment for n-acetylcysteine in B-ALL.

James Iansavitchous

B-ALL Leukemia Treatment: Exploiting Dependency on ROS to Prevent Proliferation
Région:Thames Valley
Ville:London, ON
École:A.B. Lucas S.S.
Sommaire:Investigation of genetic alterations in important antioxidant response and repair pathways in leukemic B-cells revealed a dependency in maintaining a state of oxidative stress. N-acetylcysteine effectively prevented rapid growth of the cells through reactive oxygen species scavenging, a safer mechanism than existing treatments. With established uses in the healthcare system, N-acetylcysteine can be efficiently repurposed for B-cell acute lymphoblastic leukemia treatment.

Prix Valeur
Bourse de recherche de premier cycle de l’Université d’Ottawa
Sponsor: Université d'Ottawa, Faculté des sciences
10 000,00 $
Prix d'excellence - Senior
Médaille de bronze
Sponsor: Sciences jeunesse Canada
Bourse d'admission de l'Université d'Ottawa
Médaillé de bronze, sénior – Bourse d’admission de 1 000 $
Sponsor: Université d'Ottawa
1 000,00 $
Bourse d’études de Western University
Médaillé de bronze - Bourse d'admission de 1 000 $
Sponsor: Université Western
1 000,00 $
Total12 000,00 $