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CWSF 2006 - Saguenay, Québec

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Ted Paranjothy

Novel Tumour-Specific Apoptosis-Inducing Peptide Derivatives of Apoptin
Region:Manitoba Schools Science Symposium
City:Winnipeg, MB
School:Fort Richmond Collegiate
Abstract:The objective of this project was to design small cell-penetrating peptide molecules, based on the amino acid sequence of the viral protein apoptin, that possess the ability to induce tumour-specific apoptosis. Sequences from amino acids 76-91, 82-110, and 77-121 of apoptin were found to independently induce tumour-specific apoptosis in human leukemia, lung, prostate, and breast cancer cells, when conjugated to a poly-arginine cell penetrating peptide.

Awards Value
The Manning Innovation Achievement Award
and $4000 Manning Young Canadian Innovation Award
Sponsor: Ernest C. Manning Awards Foundation
$4 000.00
UBC Science (Vancouver) Entrance Award
Senior Silver Medallist - $2000 Entrance Scholarship
Sponsor: The University of British Columbia (Vancouver)
$2 000.00
The University of Western Ontario Scholarship
Silver Medallist - $1500 Entrance Scholarship
Sponsor: University of Western Ontario
$1 500.00
Silver Medal - Biotechnology & Pharmaceutical Sciences
Sponsor: Rx&D Health Research Foundation
Total$8 200.00