| Ted Paranjothy
Novel Tumour-Specific Apoptosis-Inducing Peptide Derivatives of Apoptin
| Division: | Biotechnology | | Category: | Senior | | Region: | Manitoba Schools Science Symposium | | City: | Winnipeg, MB | | School: | Fort Richmond Collegiate | | Abstract: | The objective of this project was to design small cell-penetrating peptide molecules, based on the amino acid sequence of the viral protein apoptin, that possess the ability to induce tumour-specific apoptosis. Sequences from amino acids 76-91, 82-110, and 77-121 of apoptin were found to independently induce tumour-specific apoptosis in human leukemia, lung, prostate, and breast cancer cells, when conjugated to a poly-arginine cell penetrating peptide. |
| Awards | Value | The Manning Innovation Achievement Award
and $4000 Manning Young Canadian Innovation Award
Sponsor: Ernest C. Manning Awards Foundation | $4 000.00 | UBC Science (Vancouver) Entrance Award
Senior Silver Medallist - $2000 Entrance Scholarship
Sponsor: The University of British Columbia (Vancouver) | $2 000.00 | The University of Western Ontario Scholarship
Silver Medallist - $1500 Entrance Scholarship
Sponsor: University of Western Ontario | $1 500.00 | Silver Medal - Biotechnology & Pharmaceutical Sciences
Senior
Sponsor: Rx&D Health Research Foundation | $700.00 | | Total | $8 200.00 | |
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